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776.5.radio.agu,june77 ,just -
esen,283,pjc,
3-1121
For more than a decade it has been my conviction
that sole· reliance on measures of incident energy
by an investigator
is
the principal barrier to resolu-
tion of the thermal/nonthermal controversy
[C'f
•
Justesen and King. 19i0. with Justesen et al
.•
1971,
and Justesen, 191Sa]. Even as reliable therapeutic
quantitation of ionizing radiations was not realized
in the clinic until the concept
of
energy dosing was
introduced. the biological scientists are unlikely to
make much headway with the nonionizing radiations
until comparable measures
of
absorbed energy are
widely used and accepted.
The
number
of
investiga-
tors
of
biological effects
of
radio-frequency radia-
tion who employ dosimetric measures is on the
increase
[cf
.•
for example. Johnson
and
Guy, 1972;
Guy, 1974; Ho and Guy, 1975; Phillips et al., 1975)
but there are many who resist such measures.
Resistance to dosimetry in many instances can
be
blamed on
habit-on
the traditional reliance
on
densitometry. In a few cases, however, the argu-
ment is made that acceptance of dosimetry, which
is
predicated primarily on thermometry. thermog-
raphy. and other calorimetric measures. would
signify the investigator's acceptance
of
simple heat•
ing as the basis of any observed biological effect
of radio-frequency radiation. Definitely a
nonseq11i-
1ur,
this line
of
thinking
is
fallacious because use
of
a particular tool or method cannot commit the
user to a theoretical position. The radiologist ad-
ministers a given number
of
calorimetrically cali-
brated Rads
of
X irradiation to a patient but not
for some commensurate heating
effect-which,
quite to the contrary, he is careful
to
minimize
through use
of
filtration. Rather. having com pen•
sated for his filtration factor, he simply takes
advantage
of
the correlation between kinetic
("heating")
and photon
("ionizing")
energies.
Similarly, the use
of
a calorimetric dosimetry in
biological studies
of
radio-frequency radiation
takes
advantage of the correlation between the streni;th
of
the electromagnetic fields in a biological body
and the resulting thermal product. Instead
of
reject-
ing calorimetric techniques, the investigator
who
wishes to demonstrate effects that are not borne
of
simple heating should embrace them. One
of
the more forceful arguments that a biological
effect
is not based on simple heating would be the demon•
stration that its threshold
or
magnitude is uncorre-
lated with averaged quantities
or
rates
of
incorpo•
ration
of
radio-frequency energy. An
effect
that
is dependent, say. on peak densities
of
energy would
(or could be made to) exhibit zero-order correlations
with averaged values
of
absorbed
energy.
I hope
at
this juncture that I have clearly commu-
nicated two views: one, that systematic institution
of
dosimetry....:.measures
of
absorbed
energy-in
the laboratory should considerably advance
our
understanding of _ biological
effects
of
radio- •
frequency radiation. whatever their basis; and
two,
that low-level effects are not necessarily
of
a
nonthermal orii;in. Implicit in what I have said is
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776S,radio.agu.june77 .just
esen,283.pjc, 3-1122
another
view that has been
1
voiced before
by
'many
scientists, and disregarded: by others.
To
demon-
strate a biological effect
o~
radio-frequency radia-
tion is not perforce to demonstrate a peril.
The
criteria of a hazard arc inclusive of
but
extend
beyond the definition
of
"effect."
However.
one
should not minimize the difficulty
of
distinguishing
benign effect from hazardous effect; the distinction
may be esptcially difficult in the clinic where
destruction of a tumor by diathermy would certainly
be
hazardous for the malignancy and for
the
healthy
tissues in which it is imbedded but would be
of
significant benefit to the patient.
Differing only slightly in semantics
but
of
enor-
mous importance is another distinction, that be-
tween the class
of
thermal effects and
the
subclass
of
effects based
on
simplt heating. Excessive
(simple) heating
of
a biological body,
either
focally
or
as a whole, would appear to be the basis
of
the confirmed instances
of
biologic damage
by
radio-frequency radiations. There
are.
to
be
sure,
potenti;il nonthermal effects borne, e.g ..
of
electro-
striction and field forces [
cf
.•
for example,
Scl1wan
and
S/1tr,
1969,
and
Lin,
1976] that may hold peril,
but evidence in support
of
damage is lacking. There
is also a well-confirmed thermal effect
not
borne
of
simple heating that has recently received much
investigative attention. Originally described
by
Whitt [
1963]
and
more recently confirmed
by
Foster
and Finch [1974) is the phenomenon
of
thermoelas-
tic
upansion.
This complex heating
errect
occurs
when a pulse
of
radiation
of
high peak
density
and
sharp attack is absorbed by some medium.
The
sudden but minuscule thermalization of
the
absorb-
ing
materials-the
averaged rise
of
Celsius temper-
ature may be less than a millionth
of
a
de1:ree-be-
cause
of
the thermally-dependent densitie;
of
solids
and
liquids, launches
a
pressure wave.
It
is
now
believed by many scientists that the thermoelastic
wave
of
pressure is the basis
of
the RF-hearing
or
Frey-eHect. the perception
of
a clicking
or
""' -popping sound by a human subject whose head
intercepts a pulse
of
microwave radiation [ cf. Frty,
1965, with
Justtstn,
197Sb, and Guy.el al., 1975] •
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